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Halozyme Therapeutics
Halozyme Therapeutics
(HALO)
Halozyme Therapeutics is an American biotechnology company that develops novel oncology therapies designed to target the tumor microenvironment and licenses a novel drug delivery technology through corporate partnerships.
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Trade Name
Drug Name
Approved
Patent Expires
Indication
Hylenex recombinant
Hyaluronidase human
2005-12-02
Rheumatoid arthritis
,
Mantle-cell lymphoma
,
B-cell lymphoma
,
Lymphoid leukemia
,
Granulomatosis with polyangiitis
,
Microscopic polyangiitis
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Hyaluronidase (human recombinant)
myeloid leukemia acute
,
myeloid leukemia
,
cholangiocarcinoma
,
monocytic leukemia acute
,
castleman disease
,
burkitt lymphoma
,
multiple sclerosis
,
sclerosis
,
stomach neoplasms
,
hypercholesterolemia
,
osteoporosis
,
ovarian neoplasms
,
sarcoma
,
ovarian epithelial carcinoma
,
myelodysplastic syndromes
,
primary myelofibrosis
,
precursor cell lymphoblastic leukemia-lymphoma
,
bcr-abl positive chronic myelogenous leukemia
,
aplastic anemia
,
preleukemia
,
neoplasms
,
pancreatic neoplasms
,
hiv infections
,
non-hodgkin lymphoma
,
leukemia
,
recurrence
,
b-cell lymphoma marginal zone
,
male breast neoplasms
,
alzheimer disease
,
type 2 diabetes mellitus
,
large b-cell lymphoma diffuse
,
b-cell chronic lymphocytic leukemia
,
hereditary angioedemas
,
angioedema
,
urinary bladder neoplasms
,
hematologic neoplasms
,
prostatic neoplasms
,
hodgkin disease
,
esophageal neoplasms
,
skin neoplasms
,
cutaneous malignant melanoma
,
neoplasms by site
,
lymphoid leukemia
,
muscle spasticity
,
psoriasis
,
lymphedema
,
allergic contact dermatitis
,
dermatitis
,
contact dermatitis
,
triple negative breast neoplasms
,
heart transplantation
,
urologic neoplasms
,
transitional cell carcinoma
,
castration-resistant prostatic neoplasms
,
peripheral nervous system diseases
,
paraproteinemias
,
polyneuropathies
,
monoclonal gammopathy of undetermined significance
,
multiple myeloma
,
plasma cell neoplasms
,
breast neoplasms
,
lymphoma
,
adenocarcinoma
,
b-cell lymphoma
,
non-small-cell lung carcinoma
,
lung neoplasms
,
melanoma
,
follicular lymphoma
,
amyloidosis
,
carcinoma
,
chronic inflammatory demyelinating polyradiculoneuropathy
,
polyradiculoneuropathy
,
pancreatic ductal carcinoma
,
mantle-cell lymphoma
,
neuritis
,
immunoglobulin light-chain amyloidosis
,
pemphigus
,
bullous pemphigoid
,
myositis
,
dermatomyositis
,
muscular diseases
,
polymyositis
,
smoldering multiple myeloma
,
renal cell carcinoma
,
ductal carcinoma
,
residual neoplasm
,
pain
,
endometrial neoplasms
,
endometrioid carcinoma
,
serous cystadenocarcinoma
,
clear cell adenocarcinoma
,
carcinosarcoma
,
acinar cell carcinoma
,
mullerian mixed tumor
,
inflammatory breast neoplasms
,
healthy volunteers/patients
,
immunologic deficiency syndromes
,
primary immunodeficiency diseases
,
diabetes mellitus
,
type 1 diabetes mellitus
,
dehydration
,
cardiac output
,
rheumatoid arthritis
,
arthritis
,
covid-19
,
syndrome
,
stiff-person syndrome
,
neoplasm metastasis
,
pneumonia
,
pneumococcal pneumonia
,
invasive hydatidiform mole
,
emergencies
,
pain management
,
infertility
,
cancer pain
,
rectal neoplasms
Hyaluronate sodium
refractive surgical procedures
,
photorefractive keratectomy
Albumin
neoplasms
,
non-small-cell lung carcinoma
,
lung neoplasms
,
neoplasm metastasis
Polytetrafluoroethylene
dental implants
,
soft tissue injuries
,
urinary bladder neoplasms
,
diabetes mellitus
,
fibrosis
,
chronic kidney failure
,
renal insufficiency
,
liver cirrhosis
,
tissue adhesions
,
psoriasis
,
proctitis
,
telangiectasis
,
radiation injuries
,
pleural effusion
,
malignant pleural effusion
,
vocal cord paralysis
,
paralysis
,
anatomical pathological conditions
,
kidney diseases
,
chronic renal insufficiency
,
hyperplasia
,
alveolar bone loss
,
edentulous mouth
,
hiatal hernia
,
peri-implantitis
,
peripheral nerve injuries
,
pyloric stenosis
,
gastric outlet obstruction
,
periodontal diseases
,
hyperemia
,
osteoporosis
,
jaw fractures
,
edentulous jaw
,
hernia
,
tooth loss
,
ischemia
,
chronic limb-threatening ischemia
,
peripheral catheterization
,
inguinal hernia
,
acute coronary syndrome
,
syndrome
,
dehydration
,
ventral hernia
,
recurrence
,
postoperative complications
,
pain
,
wound infection
,
intermittent claudication
,
inflammation
,
type 1 diabetes mellitus
,
hypertension
,
heart failure
,
hemorrhage
,
tooth extraction
,
tissue preservation
,
prolapse
,
atrophy
,
peripheral arterial disease
,
peripheral vascular diseases
,
aortic dissection
,
wounds and injuries
,
infections
,
communicable diseases
,
portal hypertension
,
gastrointestinal hemorrhage
,
mucositis
,
rupture
,
blepharoptosis
,
ascites
,
biliary tract neoplasms
,
pathologic constriction
,
pelvic organ prolapse
,
renal dialysis
,
fistula
,
vascular diseases
,
aortic aneurysm
,
aortic diseases
,
otosclerosis
,
aortic arch syndromes
,
brain injuries
,
otitis media
,
otitis
,
headache
,
post-dural puncture headache
,
endoscopy
,
ankle injuries
,
sprains and strains
,
premature birth
,
schistosomiasis
,
schistosomiasis mansoni
,
incisional hernia
,
pancreatitis
,
alveolar ridge augmentation
,
hysterectomy
,
cardiomyopathies
,
dilated cardiomyopathy
,
gastroesophageal reflux
,
drug-related side effects and adverse reactions
,
gingival pocket
,
joint instability
,
reinjuries
,
bone resorption
,
aphasia
,
aphakia
,
hemolysis
,
vascular grafting
,
wound closure techniques
,
uterine prolapse
,
cystocele
,
cardiovascular diseases
,
mitral valve insufficiency
,
arteriovenous fistula
,
mesenteric ischemia
,
arteriosclerosis
,
disease
,
necrosis
,
cholangiocarcinoma
,
biliary tract diseases
,
ampulla of vater cancer
,
angiodysplasia
,
colonic polyps
,
colonic diverticulosis
,
colon diverticulum
,
diverticulum
,
coronary stenosis
,
bacteremia
,
vascular ring
,
rhinitis
,
atrophic rhinitis
,
liver diseases
,
cystic fibrosis
,
abdominal aortic aneurysm
,
aneurysm
,
dental implantation
,
single-tooth dental implants
,
immunohistochemistry
,
dental caries
,
tooth fractures
,
surgical blood loss
,
electrosurgery
,
bacterial endocarditis
,
endocarditis
,
congenital abnormalities
,
congenital heart defects
,
heart septal defects
,
ventricular heart septal defects
,
aortic valve insufficiency
,
ascending aorta dissection
,
nephrolithiasis
,
kidney calculi
,
calculi
,
dental enamel hypoplasia
,
urinary incontinence
,
menopause
,
pulmonary hypertension
,
pulmonary arterial hypertension
,
thrombosis
,
venous thrombosis
,
bacterial infections
Tiragolumab
liver neoplasms
Bococizumab
healthy volunteers/patients
,
metabolic diseases
,
metabolic syndrome
,
lipid metabolism disorders
,
hypercholesterolemia
,
dyslipidemias
,
hyperlipidemias
,
hyperlipoproteinemias
,
cardiovascular diseases
,
hyperlipoproteinemia type ii
Ademetionine
lymphoma
,
myeloid leukemia chronic-phase
,
myeloid leukemia
,
leukemia
,
bcr-abl positive chronic myelogenous leukemia
,
pancreatic neoplasms
,
carcinoma
,
vitiligo
,
b-cell lymphoma
,
glioblastoma
,
glioma
,
precursor cell lymphoblastic leukemia-lymphoma
,
lymphoid leukemia
,
colorectal neoplasms
,
breast neoplasms
,
lung neoplasms
,
squamous cell carcinoma of head and neck
,
squamous cell carcinoma
,
neoplasms
,
hidradenitis suppurativa
,
hidradenitis
,
lichen sclerosus et atrophicus
,
lichen planus
,
adenosquamous carcinoma
,
asthma
,
cholangiocarcinoma
,
polycythemia vera
,
myeloproliferative disorders
,
primary myelofibrosis
,
polycythemia
Edrecolomab
non-hodgkin lymphoma
,
lymphoma
,
b-cell lymphoma
Doconexent
neoplasms
,
breast neoplasms
,
multiple myeloma
,
b-cell chronic lymphocytic leukemia
,
lymphoid leukemia
,
non-hodgkin lymphoma
,
contraception
,
lymphoma
,
b-cell lymphoma
,
headache
,
pelvic pain
,
libido
Vorhyaluronidase alfa
alzheimer disease
Sodium chloride
fabry disease
C1 esterase inhibitor
renal insufficiency
,
delayed graft function
,
acute kidney injury
,
covid-19
,
kidney transplantation
,
graft rejection
,
myocardial infarction
,
non-st elevated myocardial infarction
,
infarction
,
ischemic stroke
,
ischemia
,
infections
,
coronavirus infections
,
communicable diseases
,
hereditary angioedemas
,
angioedema
,
inborn genetic diseases
Alunacedase alfa
esophageal neoplasms
,
adenocarcinoma
Aspartame
lymphoma
,
conjunctivitis
,
allergic rhinitis
,
rhinitis
,
allergic conjunctivitis
,
liver neoplasms
,
atopic dermatitis
,
dermatitis
,
healthy volunteers/patients
,
neoplasms
,
vomiting
,
nausea
,
infections
,
prostatic neoplasms
,
postoperative nausea and vomiting
,
recurrence
,
brain neoplasms
,
second primary neoplasms
,
depression
,
treatment-resistant depressive disorder
,
depressive disorder
,
esophageal neoplasms
,
esophageal squamous cell carcinoma
,
hematologic neoplasms
,
pneumonia
,
pseudomonas infections
,
pseudomonas aeruginosa
,
bacteremia
,
renal cell carcinoma
,
liver cirrhosis
,
experimental liver cirrhosis
,
chronic obstructive pulmonary disease
,
nasopharyngeal carcinoma
,
nasopharyngeal neoplasms
,
ovarian epithelial carcinoma
,
melanoma
,
colorectal neoplasms
,
pancreatic ductal carcinoma
,
gastrointestinal neoplasms
,
biliary tract neoplasms
,
non-small-cell lung carcinoma
,
lung neoplasms
,
hiv infections
,
carcinoma
,
acquired immunodeficiency syndrome
,
ovarian neoplasms
,
breast neoplasms
,
fibrosis
,
hepatocellular carcinoma
,
hiv-2
,
immunologic deficiency syndromes
,
hiv-1
,
antibiotic prophylaxis
,
hepatitis b
,
chronic hepatitis b
,
uterine cervical neoplasms
,
condylomata acuminata
,
coronary disease
,
coronary artery disease
,
myocardial ischemia
,
heart diseases
,
lung diseases
,
cystic fibrosis
,
pulmonary hypertension
,
pulmonary arterial hypertension
,
endometrial neoplasms
,
adenocarcinoma
,
triple negative breast neoplasms
,
asthma
,
chronic hepatitis c
,
hepatitis
,
hepatitis a
,
hypertension
,
hepatitis c
,
neuromuscular blockade
,
chronic kidney failure
,
kidney diseases
,
chronic hepatitis
,
hiv
,
intestinal diseases
,
non-hodgkin lymphoma
,
infertility
,
schizophrenia
,
traumatic brain injuries
,
brain concussion
,
brain injuries
,
post-concussion syndrome
Bevifimod
renal cell carcinoma
,
human influenza
,
nutritional status
,
pneumococcal infections
,
pneumococcal pneumonia
,
leishmaniasis
,
psoriasis
,
systemic lupus erythematosus
,
cutaneous lupus erythematosus
,
inflammatory bowel diseases
,
virus diseases
,
urticaria
,
tendon injuries
,
dermatitis
,
haemophilus influenzae
,
streptococcus pneumoniae
,
cancer pain
,
oncogenes
,
crohn disease
,
energy metabolism
,
endometrial neoplasms
,
carcinosarcoma
,
mullerian mixed tumor
,
fibrosis
,
idiopathic pulmonary fibrosis
,
pulmonary fibrosis
,
lung neoplasms
,
non-small-cell lung carcinoma
,
malaria
,
neoplasm metastasis
,
carcinoma
,
falciparum malaria
,
ovarian neoplasms
,
brain neoplasms
,
healthy volunteers/patients
,
prostatic neoplasms
,
asthma
,
recurrence
,
colorectal neoplasms
,
squamous cell carcinoma
,
multiple myeloma
,
plasma cell neoplasms
,
ovarian epithelial carcinoma
,
cutaneous malignant melanoma
,
skin neoplasms
,
type 1 diabetes mellitus
,
triple negative breast neoplasms
,
squamous cell carcinoma of head and neck
,
sickle cell anemia
,
myeloid leukemia acute
,
myeloid leukemia
,
leukemia
,
hepatitis b
,
chronic hepatitis b
,
hepatitis
,
primary myelofibrosis
,
hepatocellular carcinoma
,
liver neoplasms
,
fallopian tube neoplasms
,
pancreatic neoplasms
,
neuralgia
,
hematologic neoplasms
,
ductal carcinoma
,
circulating neoplastic cells
,
uterine neoplasms
,
uterine cervical neoplasms
,
glioma
,
streptococcus agalactiae
,
lymphoma
,
follicular lymphoma
,
neisseria meningitidis
,
haemophilus influenzae type b
,
invasive hydatidiform mole
,
biliary tract neoplasms
,
uveal neoplasms
,
respiratory tract diseases
,
respiration disorders
,
proteinuria
,
focal segmental glomerulosclerosis
,
cytomegalovirus infections
,
chronic hepatitis
,
kidney diseases
,
membranous glomerulonephritis
,
nephrotic syndrome
,
nephrosis
,
glioblastoma
,
endometrioid carcinoma
,
breast diseases
,
squamous cell neoplasms
,
neurofibromatosis 2
,
acoustic neuroma
,
neurofibromatosis 1
,
neurofibromatoses
,
neurofibroma
,
neurilemmoma
,
drug therapy
,
tuberculosis
,
pulmonary tuberculosis
,
adenocarcinoma of lung
,
disease progression
,
peritoneal neoplasms
,
inflammation
,
beta-thalassemia
,
thalassemia
,
sickle cell trait
,
essential thrombocythemia
,
polycythemia vera
,
thrombocytosis
,
polycythemia
,
ulcer
,
buruli ulcer
,
breast neoplasms
,
melanoma
,
rheumatoid arthritis
,
arthritis
,
head and neck neoplasms
,
inflammatory breast neoplasms
,
adenocarcinoma
,
respiratory syncytial virus infections
,
covid-19
,
bacterial infections
,
cellulitis
,
streptococcal infections
,
hepatitis a
,
stomach neoplasms
,
gastrointestinal neoplasms
,
digestive system neoplasms
,
infectious skin diseases
,
bacterial skin diseases
,
ductal carcinoma breast
,
renal insufficiency
,
mumps
,
measles
,
rubella
,
urinary bladder neoplasms
,
acute coronary syndrome
,
syndrome
,
rotavirus infections
,
otitis media
,
mucinous adenocarcinoma
,
meningitis
,
meningococcal meningitis
,
impetigo
,
respiratory syncytial viruses
,
herpes zoster
,
neoplasms
,
type 2 diabetes mellitus
,
diabetes mellitus
,
hiv infections
,
infections
,
acquired immunodeficiency syndrome
,
acne vulgaris
,
chronic obstructive pulmonary disease
,
communicable diseases
,
lung diseases
,
obstructive lung diseases
,
pneumonia
,
dental focal infection
,
focal infection
,
nausea
,
hiv
,
immunologic deficiency syndromes
,
ventilator-associated pneumonia
,
growth and development
,
immunologic tests
,
cognition
,
alzheimer disease
,
wasting syndrome
,
cachexia
,
dyslipidemias
,
insulin resistance
,
abdominal obesity
,
lipid metabolism
,
latent autoimmune diabetes in adults
,
community-acquired infections
,
abscess
,
folliculitis
,
staphylococcal infections
,
resistance training
,
exercise
,
depression
,
major depressive disorder
,
depressive disorder
,
thyroid neoplasms
,
papillary thyroid cancer
,
thyroid diseases
,
clostridioides difficile
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