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Halozyme Therapeutics
Halozyme Therapeutics
(HALO)
Halozyme Therapeutics is an American biotechnology company that develops novel oncology therapies designed to target the tumor microenvironment and licenses a novel drug delivery technology through corporate partnerships.
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Therapeutic Areas:
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Classification:
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Trade Name
Drug Name
Approved
Patent Expires
Indication
Hylenex recombinant
Hyaluronidase human
2005-12-02
Rheumatoid arthritis
,
Mantle-cell lymphoma
,
B-cell lymphoma
,
Lymphoid leukemia
,
Granulomatosis with polyangiitis
,
Microscopic polyangiitis
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Hyaluronidase (human recombinant)
breast neoplasms
,
non-hodgkin lymphoma
,
multiple myeloma
,
lymphoma
,
plasma cell neoplasms
,
b-cell lymphoma
,
prostatic neoplasms
,
recurrence
,
carcinoma
,
ovarian neoplasms
,
pancreatic neoplasms
,
sarcoma
,
ovarian epithelial carcinoma
,
neoplasms
,
skin neoplasms
,
melanoma
,
cutaneous malignant melanoma
,
non-small-cell lung carcinoma
,
lung neoplasms
,
covid-19
Hyaluronate sodium
erythema
,
acne vulgaris
,
cataract
,
keratoconjunctivitis sicca
,
dry eye syndromes
Albumin
renal cell carcinoma
,
colorectal neoplasms
,
non-small-cell lung carcinoma
,
melanoma
,
lymphoma
,
neoplasms
,
prostatic neoplasms
,
carcinoma
,
ovarian neoplasms
,
pancreatic neoplasms
,
aggression
,
inflammatory breast neoplasms
,
lung neoplasms
,
sarcoma
,
ovarian epithelial carcinoma
,
breast neoplasms
,
type 2 diabetes mellitus
,
diabetes mellitus
,
hyperglycemia
Polytetrafluoroethylene
dental implants
,
soft tissue injuries
,
urinary incontinence
,
urinary bladder neoplasms
,
urinary retention
,
spinal cord injuries
,
chronic kidney failure
,
atrophy
,
renal insufficiency
,
tissue adhesions
,
psoriasis
,
kidney diseases
,
proctitis
,
telangiectasis
,
radiation injuries
,
pleural effusion
,
malignant pleural effusion
,
vocal cord paralysis
,
paralysis
,
anatomical pathological conditions
,
chronic renal insufficiency
,
hyperplasia
,
alveolar bone loss
,
atherosclerosis
,
peri-implantitis
,
edentulous mouth
,
hiatal hernia
,
bone resorption
,
peripheral nerve injuries
,
pyloric stenosis
,
gastric outlet obstruction
,
periodontal diseases
,
hyperemia
,
metabolic bone diseases
,
osteoporosis
,
jaw fractures
,
edentulous jaw
,
vascular diseases
,
peripheral arterial disease
,
hernia
,
ischemia
,
diabetes mellitus
,
fibrosis
,
arterial occlusive diseases
,
peripheral vascular diseases
,
tooth loss
,
liver cirrhosis
,
chronic limb-threatening ischemia
,
hemorrhage
,
intermittent claudication
,
pancreatic neoplasms
,
gastrointestinal hemorrhage
,
bile duct neoplasms
,
peripheral catheterization
,
inguinal hernia
,
acute coronary syndrome
,
syndrome
,
hemostasis
,
dehydration
,
anodontia
,
ventral hernia
,
recurrence
,
postoperative complications
,
pain
,
wound infection
,
brain diseases
,
dental enamel hypoplasia
,
hypertension
,
portal hypertension
,
inflammation
,
pathologic constriction
,
type 1 diabetes mellitus
,
heart failure
,
tooth extraction
,
tissue preservation
,
ascites
,
prolapse
,
fistula
,
congenital heart defects
,
heart diseases
,
aneurysm
,
aortic dissection
,
wounds and injuries
,
infections
,
communicable diseases
,
mitral valve insufficiency
,
incisional hernia
,
mucositis
,
alveolar ridge augmentation
,
cardiomyopathies
,
rupture
,
blepharoptosis
,
biliary tract neoplasms
,
pelvic organ prolapse
,
renal dialysis
,
disease
,
cholangiocarcinoma
,
soft tissue infections
,
bone density
,
aortic aneurysm
,
aortic diseases
,
otosclerosis
,
heart septal defects
,
aortic arch syndromes
,
nephrolithiasis
,
kidney calculi
,
brain injuries
,
otitis media
,
otitis
,
headache
,
post-dural puncture headache
,
endoscopy
,
ankle injuries
,
sprains and strains
,
premature birth
,
schistosomiasis
,
schistosomiasis mansoni
,
neoplasms
,
pancreatitis
,
hysterectomy
,
dilated cardiomyopathy
,
gastroesophageal reflux
,
drug-related side effects and adverse reactions
,
gingival pocket
,
joint instability
,
reinjuries
,
aphasia
,
aphakia
,
hemolysis
,
vascular grafting
,
wound closure techniques
,
uterine prolapse
,
cystocele
,
cardiovascular diseases
,
arteriovenous fistula
,
mesenteric ischemia
,
arteriosclerosis
,
necrosis
,
biliary tract diseases
,
ampulla of vater cancer
,
angiodysplasia
,
colonic polyps
,
colonic diverticulosis
,
colon diverticulum
,
diverticulum
,
coronary stenosis
,
bacteremia
,
vascular ring
,
rhinitis
,
atrophic rhinitis
,
bone regeneration
,
surgical wound
,
surgical wound dehiscence
,
corneal ulcer
,
bile duct diseases
,
intracranial aneurysm
,
carotid-cavernous sinus fistula
,
periodontal debridement
,
long qt syndrome
,
ventricular tachycardia
,
tachycardia
,
ventricular fibrillation
,
arteritis
,
liver diseases
,
cystic fibrosis
,
abdominal aortic aneurysm
,
dental implantation
,
single-tooth dental implants
,
immunohistochemistry
,
dental caries
,
tooth fractures
,
surgical blood loss
,
electrosurgery
,
obesity
,
bacterial endocarditis
,
endocarditis
,
congenital abnormalities
,
ventricular heart septal defects
,
aortic valve stenosis
,
bone transplantation
,
atrial heart septal defects
,
aortic valve insufficiency
,
ascending aorta dissection
,
hypertrophy
,
calculi
,
menopause
,
pulmonary hypertension
,
pulmonary arterial hypertension
,
thrombosis
,
venous thrombosis
,
periodontitis
,
bacterial infections
,
percutaneous nephrolithotomy
,
oral surgery
,
virus diseases
,
color
Tiragolumab
colorectal neoplasms
,
breast neoplasms
,
triple negative breast neoplasms
,
adenocarcinoma
,
squamous cell carcinoma of head and neck
,
small cell carcinoma
,
uterine cervical neoplasms
,
urologic neoplasms
,
urinary bladder neoplasms
,
transitional cell carcinoma
,
pancreatic neoplasms
,
stomach neoplasms
,
rectal neoplasms
,
melanoma
,
non-hodgkin lymphoma
,
lymphoma
,
follicular lymphoma
,
b-cell lymphoma
,
head and neck neoplasms
,
renal cell carcinoma
,
recurrence
,
microsatellite instability
,
carcinoma
,
non-small-cell lung carcinoma
,
lung neoplasms
,
squamous cell carcinoma
,
neoplasms
,
small cell lung carcinoma
,
liver neoplasms
,
esophageal neoplasms
,
hepatocellular carcinoma
,
esophageal squamous cell carcinoma
Gilvetmab
lung neoplasms
,
small cell lung carcinoma
,
neoplasms
,
melanoma
,
urinary bladder neoplasms
,
esophageal squamous cell carcinoma
,
triple negative breast neoplasms
,
malignant mesothelioma
,
mesothelioma
,
breast neoplasms
,
glioblastoma
,
colorectal neoplasms
,
carcinoma
,
esophageal neoplasms
,
squamous cell carcinoma
,
pancreatic neoplasms
,
tumor virus infections
,
non-small-cell lung carcinoma
Bococizumab
hypercholesterolemia
,
healthy volunteers/patients
Maxacalcitol
esophageal neoplasms
,
adenocarcinoma
,
recurrence
,
breast neoplasms
,
hepatitis c
,
hepatitis
,
hepatitis a
,
macular edema
,
macular degeneration
,
carcinoma
,
hepatocellular carcinoma
,
wet macular degeneration
Edrecolomab
hypertension
,
hiv infections
,
hiv
,
acquired immunodeficiency syndrome
,
immunologic deficiency syndromes
,
urinary bladder neoplasms
,
ureteral neoplasms
,
neoplasm metastasis
,
neoplasms
,
non-small-cell lung carcinoma
,
lung neoplasms
,
breast neoplasms
,
renal cell carcinoma
,
urologic neoplasms
,
carcinoma
,
stomach neoplasms
,
head and neck neoplasms
,
melanoma
,
hepatitis c
,
chronic hepatitis c
,
hepatitis
,
hepatitis a
,
malignant mesothelioma
,
mesothelioma
,
lymphoma
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
transitional cell carcinoma
,
invasive hydatidiform mole
Doconexent
ovarian neoplasms
,
fallopian tube neoplasms
,
ovarian epithelial carcinoma
,
lung neoplasms
,
lymphoma
,
b-cell chronic lymphocytic leukemia
,
lymphoid leukemia
,
non-small-cell lung carcinoma
,
non-hodgkin lymphoma
,
leukemia
,
esophageal neoplasms
,
respiratory distress syndrome
,
acute lung injury
,
newborn respiratory distress syndrome
,
syndrome
,
urologic neoplasms
,
transitional cell carcinoma
,
neoplasms
,
multiple myeloma
,
breast neoplasms
,
follicular lymphoma
,
b-cell lymphoma
,
adenocarcinoma
,
biliary tract neoplasms
,
gallbladder neoplasms
,
precancerous conditions
,
peripheral nervous system diseases
,
paraproteinemias
,
monoclonal gammopathy of undetermined significance
,
pancreatic neoplasms
,
head and neck neoplasms
,
mantle-cell lymphoma
,
kidney diseases
,
iga glomerulonephritis
Vorhyaluronidase alfa
neoplasms
,
neoplasms by site
,
urologic neoplasms
,
transitional cell carcinoma
,
multiple myeloma
,
plasma cell neoplasms
,
melanoma
,
carcinoma
,
renal cell carcinoma
Sodium chloride
healthy volunteers/patients
,
neoplasms
,
heart failure
,
colorectal neoplasms
,
chronic renal insufficiency
,
kidney diseases
,
cystic fibrosis
,
cholangiocarcinoma
,
biliary tract neoplasms
,
gallbladder neoplasms
,
drug-related side effects and adverse reactions
,
renal insufficiency
,
cardiovascular diseases
,
type 2 diabetes mellitus
,
major depressive disorder
,
depressive disorder
,
diabetes mellitus
,
non-small-cell lung carcinoma
,
depression
,
chronic obstructive pulmonary disease
,
obstructive lung diseases
,
sepsis
,
septic shock
,
shock
,
toxemia
,
treatment-resistant depressive disorder
,
lung diseases
,
hidradenitis suppurativa
,
hidradenitis
,
small cell carcinoma
,
obesity
,
fibrosis
,
non-alcoholic fatty liver disease
,
fatty liver
,
hypersensitivity
,
syndrome
,
drug hypersensitivity syndrome
,
carcinoma
,
lung neoplasms
,
hepatocellular carcinoma
,
liver neoplasms
,
small cell lung carcinoma
,
sars-cov-2
,
respiratory tract infections
,
asthma
,
vasculitis
,
churg-strauss syndrome
,
recurrence
,
ovarian neoplasms
,
ovarian epithelial carcinoma
,
gastroesophageal reflux
,
peptic esophagitis
,
esophagitis
,
infections
,
respiratory syncytial virus infections
,
coronavirus infections
,
coronavirus
,
hematologic diseases
,
hypereosinophilic syndrome
,
eosinophilia
,
leukocyte disorders
,
uterine cervical neoplasms
,
covid-19
,
hypertension
,
breast neoplasms
,
postoperative pain
C1 esterase inhibitor
renal insufficiency
,
delayed graft function
,
acute kidney injury
,
covid-19
,
kidney transplantation
,
graft rejection
,
myocardial infarction
,
non-st elevated myocardial infarction
,
infarction
,
ischemic stroke
,
ischemia
,
infections
,
coronavirus infections
,
communicable diseases
,
hereditary angioedemas
,
angioedema
,
inborn genetic diseases
Alunacedase alfa
esophageal neoplasms
,
adenocarcinoma
Aspartame
tuberculosis
,
neoplasms
,
leukemia
,
myeloid leukemia acute
,
myeloid leukemia
,
deficiency diseases
,
paraproteinemias
,
hiv infections
,
precursor cell lymphoblastic leukemia-lymphoma
,
lymphoid leukemia
,
breast neoplasms
,
immune system diseases
,
hematologic neoplasms
,
type 2 diabetes mellitus
,
uveitis
,
metabolic diseases
,
disease
,
lipidoses
,
immunoglobulin g4-related disease
,
malaria
,
falciparum malaria
,
whooping cough
,
tetanus
,
diphtheria
,
tetany
,
polycystic kidney diseases
,
autosomal dominant polycystic kidney
,
arthrogryposis
,
renal insufficiency
,
hematologic diseases
,
blood protein disorders
,
neoplasms by histologic type
,
prostatic neoplasms
,
circulating neoplastic cells
,
heart transplantation
,
non-small-cell lung carcinoma
,
lung neoplasms
,
carcinoma
,
nasopharyngeal carcinoma
,
nasopharyngeal neoplasms
,
esophageal neoplasms
,
adenocarcinoma
,
neoplasm metastasis
,
anemia
,
aplastic anemia
,
multiple myeloma
,
plasma cell neoplasms
,
hypercholesterolemia
,
hyperlipoproteinemia type ii
,
meningococcal infections
,
hemolytic anemia autoimmune
,
meningitis
,
meningococcal meningitis
,
stomach neoplasms
,
hemophilia a
,
kidney diseases
,
gaucher disease
,
smoldering multiple myeloma
,
hemophilia b
,
chronic renal insufficiency
,
hyperphosphatemia
,
multiple sclerosis
,
sclerosis
,
homozygous familial hypercholesterolemia
,
pharyngitis
,
tonsillitis
,
healthy volunteers/patients
,
asthma
,
glycogen storage disease type ii
,
glycogen storage disease
,
atopic dermatitis
,
dermatitis
,
lymphoma
,
eczema
,
diabetes mellitus
,
hyperglycemia
,
glycogen storage disease type iii
,
non-hodgkin lymphoma
,
osteoporosis
,
postmenopausal osteoporosis
,
lymphoproliferative disorders
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