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Halozyme Therapeutics
Halozyme Therapeutics
(HALO)
Halozyme Therapeutics is an American biotechnology company that develops novel oncology therapies designed to target the tumor microenvironment and licenses a novel drug delivery technology through corporate partnerships.
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Therapeutic Areas:
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Trade Name
Drug Name
Approved
Patent Expires
Indication
Hylenex recombinant
Hyaluronidase (human recombinant)
2005-12-02
Rheumatoid arthritis
,
Mantle-cell lymphoma
,
B-cell lymphoma
,
Lymphoid leukemia
,
Granulomatosis with polyangiitis
,
Microscopic polyangiitis
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Hyaluronidase (human recombinant)
myeloid leukemia acute
,
multiple sclerosis
,
cholangiocarcinoma
,
monocytic leukemia acute
,
myeloid leukemia
,
liver neoplasms
,
kidney neoplasms
,
castleman disease
,
sclerosis
,
stomach neoplasms
,
hypercholesterolemia
,
osteoporosis
,
ovarian neoplasms
,
sarcoma
,
acquired immunodeficiency syndrome
,
myelodysplastic syndromes
,
primary myelofibrosis
,
precursor cell lymphoblastic leukemia-lymphoma
,
bcr-abl positive chronic myelogenous leukemia
,
hodgkin disease
,
aplastic anemia
,
hepatocellular carcinoma
,
small cell lung carcinoma
,
chronic progressive multiple sclerosis
,
pancreatic neoplasms
,
hiv infections
,
neoplasm metastasis
,
non-hodgkin lymphoma
,
lung neoplasms
,
urinary bladder neoplasms
,
male breast neoplasms
,
amyloidosis
,
leukemia
,
alzheimer disease
,
recurrence
,
type 2 diabetes mellitus
,
hereditary angioedemas
,
hematologic neoplasms
,
prostatic neoplasms
,
relapsing-remitting multiple sclerosis
,
esophageal neoplasms
,
cutaneous malignant melanoma
,
neoplasms by site
,
lymphoproliferative disorders
,
stroke
,
muscle spasticity
,
cerebral palsy
,
abnormal reflex
,
psoriasis
,
lymphedema
,
allergic contact dermatitis
,
dermatitis
,
contact dermatitis
,
triple negative breast neoplasms
,
heart transplantation
,
brain neoplasms
,
urologic neoplasms
,
transitional cell carcinoma
,
castration-resistant prostatic neoplasms
,
peripheral nervous system diseases
,
monoclonal gammopathy of undetermined significance
,
squamous cell neoplasms
,
head and neck neoplasms
,
plasma cell leukemia
,
neoplasms
,
breast neoplasms
,
non-small-cell lung carcinoma
,
b-cell lymphoma
,
follicular lymphoma
,
plasma cell neoplasms
,
melanoma
,
immunoglobulin light-chain amyloidosis
,
b-cell lymphoma marginal zone
,
chronic inflammatory demyelinating polyradiculoneuropathy
,
large b-cell lymphoma diffuse
,
pancreatic ductal carcinoma
,
adenocarcinoma
,
mantle-cell lymphoma
,
lymphoma
,
b-cell chronic lymphocytic leukemia
,
skin neoplasms
,
burkitt lymphoma
,
renal cell carcinoma
,
polyradiculoneuropathy
,
pemphigus
,
bullous pemphigoid
,
patient preference
,
waldenstrom macroglobulinemia
,
smoldering multiple myeloma
,
ductal carcinoma
,
pain
,
endometrial neoplasms
,
endometrioid carcinoma
,
acinar cell carcinoma
,
inflammatory breast neoplasms
,
myositis
,
dermatomyositis
,
polymyositis
,
reactive arthritis
,
multiple myeloma
,
healthy volunteers/patients
,
primary immunodeficiency diseases
,
immunologic deficiency syndromes
,
type 1 diabetes mellitus
,
insulin resistance
,
dehydration
,
diabetes mellitus
,
cardiac output
,
rheumatoid arthritis
,
arthritis
,
syndrome
,
stiff-person syndrome
,
neuritis
,
pneumonia
,
pneumococcal pneumonia
,
invasive hydatidiform mole
,
emergencies
,
pain management
,
agnosia
,
infertility
,
cancer pain
,
rectal neoplasms
,
knee osteoarthritis
Hyaluronate sodium
acute pain
Polytetrafluoroethylene
diabetes mellitus
Tiragolumab
colorectal neoplasms
,
triple negative breast neoplasms
,
squamous cell carcinoma of head and neck
,
breast neoplasms
,
small cell carcinoma
,
uterine cervical neoplasms
,
urologic neoplasms
,
urinary bladder neoplasms
,
transitional cell carcinoma
,
pancreatic neoplasms
,
stomach neoplasms
,
rectal neoplasms
,
melanoma
,
non-hodgkin lymphoma
,
lymphoma
,
follicular lymphoma
,
b-cell lymphoma
,
carcinoma
,
squamous cell carcinoma
,
renal cell carcinoma
,
recurrence
,
microsatellite instability
,
non-small-cell lung carcinoma
,
small cell lung carcinoma
,
liver neoplasms
,
neoplasms
,
esophageal neoplasms
,
hepatocellular carcinoma
,
esophageal squamous cell carcinoma
Gilvetmab
lung neoplasms
,
small cell lung carcinoma
,
neoplasms
,
melanoma
,
urinary bladder neoplasms
,
esophageal squamous cell carcinoma
,
triple negative breast neoplasms
,
malignant mesothelioma
,
breast neoplasms
,
glioblastoma
,
colorectal neoplasms
,
pancreatic neoplasms
,
neoplasm metastasis
,
tumor virus infections
,
non-small-cell lung carcinoma
Bococizumab
healthy volunteers/patients
,
metabolic diseases
,
metabolic syndrome
,
lipid metabolism disorders
,
hypercholesterolemia
,
dyslipidemias
,
hyperlipidemias
,
hyperlipoproteinemias
,
cardiovascular diseases
,
hyperlipoproteinemia type ii
Maxacalcitol
esophageal neoplasms
,
recurrence
,
breast neoplasms
,
hepatitis c
,
hepatitis
,
hepatitis a
,
macular edema
,
macular degeneration
,
hepatocellular carcinoma
Edrecolomab
chronic renal insufficiency
,
atopic dermatitis
,
eczema
,
asthma
,
neoplasms
,
chronic obstructive pulmonary disease
,
psoriasis
,
relapsing-remitting multiple sclerosis
Doconexent
neoplasms
,
ovarian neoplasms
,
pancreatic neoplasms
,
non-small-cell lung carcinoma
,
head and neck neoplasms
,
lung neoplasms
,
sarcoma
,
urinary bladder neoplasms
,
unknown primary neoplasms
,
juvenile arthritis
,
arthritis
,
metabolic syndrome
,
syndrome
,
multiple myeloma
,
breast neoplasms
,
colorectal neoplasms
,
recurrence
,
plasma cell neoplasms
,
squamous cell carcinoma of head and neck
,
esophageal neoplasms
,
esophageal squamous cell carcinoma
,
ulcerative colitis
,
colitis
,
ulcer
,
male breast neoplasms
,
covid-19
,
human influenza
,
lymphoma
,
non-hodgkin lymphoma
,
large b-cell lymphoma diffuse
,
inflammation
Aspartame
lymphoma
,
conjunctivitis
,
allergic rhinitis
,
rhinitis
,
allergic conjunctivitis
,
liver neoplasms
,
atopic dermatitis
,
dermatitis
,
neoplasm metastasis
,
healthy volunteers/patients
,
neoplasms
,
prostatic neoplasms
,
vomiting
,
nausea
,
infections
,
esophageal neoplasms
,
postoperative nausea and vomiting
,
soft tissue neoplasms
,
brain neoplasms
,
second primary neoplasms
,
treatment-resistant depressive disorder
,
esophageal squamous cell carcinoma
,
renal cell carcinoma
,
experimental liver cirrhosis
,
chronic obstructive pulmonary disease
,
nasopharyngeal carcinoma
,
nasopharyngeal neoplasms
,
recurrence
,
melanoma
,
colorectal neoplasms
,
pancreatic ductal carcinoma
,
biliary tract neoplasms
,
non-muscle invasive bladder neoplasms
,
non-small-cell lung carcinoma
,
hiv infections
,
carcinoma
,
lung neoplasms
,
ovarian neoplasms
,
uterine cervical neoplasms
,
triple negative breast neoplasms
,
breast neoplasms
,
condylomata acuminata
,
hepatocellular carcinoma
,
hiv-2
,
immunologic deficiency syndromes
,
hiv-1
,
antibiotic prophylaxis
,
hepatitis b
,
chronic hepatitis b
,
ovarian epithelial carcinoma
,
coronary disease
,
coronary artery disease
,
myocardial ischemia
,
heart diseases
,
fibrosis
,
lung diseases
,
cystic fibrosis
,
pulmonary hypertension
,
pulmonary arterial hypertension
,
endometrial neoplasms
,
fallopian tube neoplasms
,
urinary bladder neoplasms
,
acquired immunodeficiency syndrome
,
asthma
,
chronic hepatitis c
,
hepatitis
,
hepatitis a
,
hepatitis c
,
hiv
,
neuromuscular blockade
,
hematologic neoplasms
,
hematopoietic stem cell transplantation
,
pneumonia
,
pseudomonas infections
,
pseudomonas aeruginosa
,
gram-negative bacterial infections
,
bacteremia
,
chronic kidney failure
,
kidney diseases
,
chronic hepatitis
,
intestinal diseases
,
hypertension
,
non-hodgkin lymphoma
,
infertility
,
schizophrenia
,
traumatic brain injuries
,
brain concussion
,
brain injuries
,
post-concussion syndrome
,
papillomavirus infections
,
uterine cervical dysplasia
Bevifimod
relapsing-remitting multiple sclerosis
,
laron syndrome
,
pituitary dwarfism
,
pituitary diseases
Nadide
neoplasms
,
breast neoplasms
,
non-hodgkin lymphoma
,
colorectal neoplasms
Nepidermin
postoperative nausea and vomiting
,
plasmacytoma
,
viral hepatitis human
,
psoriasis
,
neurologic manifestations
,
brain neoplasms
,
neoplasms
,
lymphoma
,
biliary tract neoplasms
,
glioma
,
follicular lymphoma
,
asthma
,
squamous cell neoplasms
,
large cell carcinoma
,
chronic obstructive pulmonary disease
,
lung diseases
,
cholangiocarcinoma
,
glioblastoma
,
mouth neoplasms
,
oropharyngeal neoplasms
,
laryngeal neoplasms
,
hypopharyngeal neoplasms
,
b-cell lymphoma marginal zone
,
mantle-cell lymphoma
,
endometrial neoplasms
,
transitional cell carcinoma
,
uterine cervical neoplasms
,
neuroendocrine carcinoma
,
type 2 diabetes mellitus
,
diabetes mellitus
,
non-small-cell lung carcinoma
,
hepatitis c
,
hepatitis
,
hepatitis a
,
breast neoplasms
,
infections
,
communicable diseases
,
chronic hepatitis c
,
neoplasm metastasis
,
lung neoplasms
,
melanoma
,
vomiting
,
hiv infections
,
triple negative breast neoplasms
,
colorectal neoplasms
,
stomach neoplasms
,
esophageal neoplasms
,
nausea
,
head and neck neoplasms
,
ovarian neoplasms
,
osteoporosis
,
chronic hepatitis
,
dyslipidemias
,
adenocarcinoma
,
squamous cell carcinoma of head and neck
,
sleep initiation and maintenance disorders
,
clostridium infections
,
multiple myeloma
,
plasma cell neoplasms
,
squamous cell carcinoma
,
hodgkin disease
,
recurrence
,
ovarian epithelial carcinoma
,
migraine disorders
,
castration-resistant prostatic neoplasms
,
pancreatic neoplasms
,
hypertension
,
essential hypertension
,
nasopharyngeal neoplasms
,
acquired immunodeficiency syndrome
,
hiv
,
chronic renal insufficiency
,
kidney diseases
,
carcinoma
,
hepatocellular carcinoma
,
general anesthesia
,
neuromuscular blockade
,
intraabdominal infections
,
urinary tract infections
,
malignant mesothelioma
,
mesothelioma
,
postmenopausal osteoporosis
,
hypercholesterolemia
,
alzheimer disease
,
tuberculosis
,
erectile dysfunction
,
renal cell carcinoma
,
surgical wound infection
,
bacterial skin diseases
,
bacterial infections
,
staphylococcal infections
,
hiv-2
,
immunologic deficiency syndromes
,
urinary bladder neoplasms
,
diabetic foot
,
type 1 diabetes mellitus
,
cytomegalovirus infections
,
disease
,
glucose metabolism disorders
,
metabolic diseases
,
endocrine system diseases
,
allergic rhinitis
,
rhinitis
,
allergic rhinitis seasonal
,
liver neoplasms
,
fallopian tube neoplasms
,
pyelonephritis
,
pneumonia
,
bacterial pneumonia
,
heart failure
,
low back pain
,
back pain
,
liver failure
,
hepatic insufficiency
,
hepacivirus
,
prostatic hyperplasia
,
anesthesia
,
amnesia
,
cognitive dysfunction
,
obesity
,
overweight
,
prostatic neoplasms
,
plexiform neurofibroma
,
neurofibromatosis 1
,
hereditary breast and ovarian cancer syndrome
,
brca2 genes
,
central nervous system neoplasms
,
nervous system neoplasms
,
rheumatoid arthritis
,
arthritis
,
hip osteoarthritis
,
surgical blood loss
,
replacement arthroplasty hip
Pegvorhyaluronidase alfa
non-small-cell lung carcinoma
,
cholangiocarcinoma
,
recurrence
,
stomach neoplasms
,
pancreatic neoplasms
,
neoplasms
,
esophageal neoplasms
,
breast neoplasms
,
pancreatic ductal carcinoma
,
adenocarcinoma
,
ductal carcinoma
,
thromboembolism
Polyglycolic acid
pancreatic neoplasms
,
hereditary sensory and autonomic neuropathies
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